Effect of overweight and obesity on spirometric parameters in children and adolescent with asthma

Aim: Being overweight and obesity are factors in the negative modification of bronchial asthma (BA). The mechanisms aggravating effect on course BA have not yet been fully determined, but include changes external respiration. aim study was to being overweight/obesity spirometric parameters occurrence dysanapsis children adolescents with BA. Methods: It a cross-sectional, open, single-center study. data were obtained from 428 patients atopic aged 7 years 17 years, 12.0 [9.0; 14.0], 72.9% (312/428) them boys. divided into 3 groups: group 1—normal body weight; 2—overweight; 3—obesity. All participants underwent spirometry, ratio forced expiratory volume 1 second (FEV1)/forced vital capacity (FVC) calculated diagnosis performed. Results: As weight increases, progressive decrease FEV1/FVC is revealed—group 1: 79.55% [71.37; 85.43]; 2: 76.82% [70.12; 82.03]; 3: 76.28% [67.04; 79.89] P = 0.004; as well Z FEV1/FVC: 1—1.23 [–2.18; –0.28]; 2—1.54 [–2.19; –0.68]; 3—1.75 [–2.63; –0.90] 0.02. Dysanapsis detected 37.7% (159/428) patients. incidence increased statistically significantly increasing mass index (BMI) amounted to: normal weight—31.7% (77/243), overweight—42.0% (55/131), obesity—50% (27/54) 0.016. Conclusions: In BA, BMI there significant FEV1/FVC, and, consequently, patency; also increases significantly. Taken together, this indicates formation an obstructive pattern respiration under influence